Bioinformatics Lab
@
Machine Intelligence Unit, Indian Statistical Institute
Kolkata 700108
Web Server
1. AMOSA-TargetMiner: A novel multi objective optimization based miRNA-target prediction method
3. TargetMiner: microRNA target prediction tool
Prediction of microRNA (miRNA) target mRNAs using machine learning approaches is an important area of research. However, most of the methods suffer from either high false positive or false negative rates. One reason for this is the marked deficiency of negative examples or miRNA-non target pairs. Systematic identification of non-target mRNAs is still not addressed properly, and therefore, current machine learning approaches are compelled to rely on artificially generated negative examples for training. ....more
Ref: Sanghamitra Bandyopadhyay and Ramkrishna Mitra, Targetminer: MicroRNA Target Prediction with Systematic Identification Of Tissue Specific Negative Examples, Bioinformatics, 2009, doi: 10.1093/bioinformatics/btp503.